Difference between revisions of "Bay11-7085"
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| + | # Krishnan, N., G. Bencze, et al. (2013). The anti-inflammatory compound BAY-11-7082 is a potent inhibitor of protein tyrosine phosphatases. Febs J 280(12): 2830-2841.[https://www.ncbi.nlm.nih.gov/pubmed/?term=23578302 23578302]<br/> | ||
| + | # Pierce, J. W., R. Schoenleber, et al. (1997). Novel inhibitors of cytokine-induced IkappaBalpha phosphorylation and endothelial cell adhesion molecule expression show anti-inflammatory effects in vivo. J Biol Chem 272(34): 21096-21103. [https://www.ncbi.nlm.nih.gov/pubmed/?term=9261113 9261113]<br/> | ||
[[Category:Ligands|Ligands]][[Category:Tyrosine-protein phosphatase non-receptor type 1|Tyrosine-protein phosphatase non-receptor type 1]] | [[Category:Ligands|Ligands]][[Category:Tyrosine-protein phosphatase non-receptor type 1|Tyrosine-protein phosphatase non-receptor type 1]] | ||
Revision as of 20:02, 24 July 2019
| Basic Information | |
|---|---|
| CAS Number | 196309-76-9 |
| Molecular Formula | C13H15NO2S |
| Molecular Weight | 249.33 g/mol |
| PubChem CID | 5353432 |
| Type | Synthetic |
| Bond Type | Carbon-Sulfur Bond: Michael addition |
Molecular Structure
Name and Identifier
- SMILES
- CC(C)(C)C1=CC=C(C=C1)S(=O)(=O)C=CC#N
- Chemical Name/Synonyms
- 3-((4-(1,1-dimethylethyl)phenyl)sulfonyl)-2-propenenitrile
- (E)-3-(4-Tert-butylphenylsulfonyl)acrylonitrile
Cysteinome Target
Related PDB
- Unknown
Property and Activity
Reference
- Krishnan, N., G. Bencze, et al. (2013). The anti-inflammatory compound BAY-11-7082 is a potent inhibitor of protein tyrosine phosphatases. Febs J 280(12): 2830-2841.23578302
- Pierce, J. W., R. Schoenleber, et al. (1997). Novel inhibitors of cytokine-induced IkappaBalpha phosphorylation and endothelial cell adhesion molecule expression show anti-inflammatory effects in vivo. J Biol Chem 272(34): 21096-21103. 9261113
